Antibiotics cure tuberculosis (TB) in 95 percent of cases. Usually, you must take antibiotics for several months; if you stop early, a few TB bacteria may survive and make you sick again. Doctors usually prescribe isoniazid, pyrazinamide, ethambutol (Myambutol), rifampin (Rifadin), or a combination of these medications, just in case the particular strain of TB is resistant to one or two of them. However, certain strains of very drug-resistant TB cannot be cured. In these rare cases, the disease can be fatal.