Another drug called psoralen is also commonly used in combination with light therapy to restore color to depigmented skin, a treatment called PUVA therapy. Psoralen can be taken orally as a pill or applied to the skin. PUVA therapy is about 50 to 75 percent effective in restoring color to the trunk, upper arms, upper legs, and face, but much less effective when used on the hands and feet, according to the American Academy of Dermatology.
Some people who have lost most of their skin color may opt for depigmenting the rest of their skin. In these cases, doctors may recommend use of topical creams that can remove pigment from skin.