Any bone marrow transplant is risky because complications, such as severe infections and immune system problems, can occur.
- If the recipient's natural defense (immune) system isn't weakened enough by the medicines given before the transplant, it can attack the new stem cells and cause the transplant to fail.
- If the donor's stem cells don't match the recipient's closely enough, the donor's new immune system cells may attack certain organs in the recipient (graft-versus-host disease).
- Other complications can include seizures and bleeding in the brain.
In some cases, this disease can cause long-term sickness or death (about 5% to 10% of bone marrow transplant recipients die).A person may be unable to have children (infertile) after a bone marrow transplant.
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