Most of the time, low sex drive is a temporary condition. A variety of factors such as hormone changes, illness, depression, stress, and relationship issues may lead to low libido. Many of these factors can be treated with lifestyle changes, counseling, and sometimes the help of a doctor. In general, sex drive fluctuates throughout a person's life, and a person may go through many different levels of sexual desire. If you're experiencing lasting lack of interest in sex, talk to a doctor to find solutions.