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Good In Bed answeredBased on its proximity to one's nether regions, it's no surprise that colorectal cancer can easily affect one's intimate life. Both a tumor, and the cancer treatment itself, can put pressure on the vaginal walls, making penetration painful. Treatment may also damage the nerves in the pelvic area, making it more difficult to experience pleasure. This could -- in turn -- lead to erectile dysfunction or ejaculation issues in men. In addition, the presence of a stoma and colostomy bag could affect one's body image, and also make sexual activity challenging.