No, ibuprofen does not contain aspirin. Ibuprofen and aspirin are two different types of NSAIDs (non-steroid anti-inflammatory drugs) that can be used to treat similar conditions. Aspirin is also in a family of medicine called salicylates. When taking both types of medications, it's important to take ibuprofen at least eight hours before or 30 minutes after aspirin, otherwise ibuprofen can reduce the effectiveness of aspirin. If you are allergic or sensitive to ibuprofen, your doctor may have you take aspirin to reduce fever or as a treatment for body aches. Do not take a cough or cold medicine that contains aspirin or ibuprofen without first talking to your doctor.