Question

Multiple Sclerosis Treatment

What medications can help treat pseudobulbar affect if I have MS?

A Answers (1)

  • Once your doctor has given you a diagnosis of pseudobulbar affect (PBA) -- episodes of uncontrollable laughing and/or crying that may be inappropriate -- you may be a candidate for Nuedexta. This oral medication (in capsule form, taken twice daily) is a combination of the generic drug quinidine, which prevents heart arrhythmia, and the cough suppressant dextromethorphan.

    If you think you may be a candidate for this medication, talk with your doctor about your options. In the past, tricyclic anti-depressants (such as amitriptyline and nortriptylene) and selective serotonin reuptake inhibitors (such as Prozac, Paxil, Zoloft, Celexa, and Lexapro) have been used to treat PBA, although with only modest success.
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