A Answers (1)
Stacy Wiegman, PharmD, Pharmacy, answeredMetformin by itself is unlikeley to cause kidney damage, but it is known to be excreted by the kidneys. People with kidney diseases may have problems eliminating metformin from their bodies. Metformin should not be used in people with kidney disease because of increased risk of metformin accumulation and lactic acidosis. The higher the degree of kidney impairment, the higher the risk is.