Lipid storage disorders are almost all very serious. Most children born with lipid storage disorders develop serious symptoms such as neurological impairment, organ damage or failure, and severe health complications within a few years. Some forms of lipid storage diseases are usually fatal within a year, while other can persist for periods of years to decades. All require careful management of symptoms and side effects, especially because there are so few treatments available. However, the most common forms of lipid storage disorders, Gaucher disease types 1 and 3, have an effective treatment in enzyme replacement.