One good reason to store the insulin you’re using at room temperature is that injecting cold insulin can make the injection feel more uncomfortable. If your insulin is cold, draw it up into the syringe, then warm it up by gently rolling it back and forth in your hands.
If you are traveling and keep your insulin stored in a cooler, make sure the insulin doesn’t freeze or come in contact with ice. Storing insulin at temperatures colder than 36 degrees Fahrenheit can cause it to lose potency and clump. Also avoid getting insulin too hot or leaving it in direct sunlight for too long. Insulin can spoil if it gets hotter than 86 degrees Fahrenheit. The general rule of thumb is, if the temperature is comfortable for you, your insulin will be okay, too.