Mixed connective tissue disease (MCTD) can range from mild cases with only occasional flare ups, to more severe cases in which daily medication and regular monitoring are necessary. The most serious complications of MCTD include high blood pressure that adversely affects the lungs, known as pulmonary hypertension, and heart disease. Medications and routine monitoring with an electrocardiogram may be necessary to help control these conditions in some people.
There are also serious side effects that come along with long-term use of the most common MCTD treatment - corticosteroids. Your doctor will need to monitor you for these risks, such as bone loss, infection, and muscle weakness. Finally, there may be a danger of complications in pregnancy, such as flare ups or having a low birth weight baby, for women with MCTD.