Hypogonadism describes a condition in which the sex glands do not produce a normal or sufficient amount of hormones. The condition can affect both men and women; the hormones and glands involved vary by sex. In men, the glands are the testes, or testicles, and the hormone is testoerone. In women, the glands are the ovaries, and the hormone is estrogen. Congenital hypogonadism refers to a situation in which the condition is present at birth, rather than acquired later in life.