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Bryce B. Wylde, Alternative & Complementary Medicine, answeredDevil's claw is a native plant of southern Africa (especially in the Kalahari Desert), Namibia, and Madagascar. It has been traditionally used an anti-inflammatory and analgesic. Devil's Claw has been very effective in clinical trials to reduce chronic pain associated with the lower back, osteoarthritis, rheumatoid arthritis, and fibromyalgia! No wonder it is a common ingredient in many joint formulas!Helpful? 2 people found this helpful.