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Stacy Wiegman, PharmD, Pharmacy, answeredEstroven comes in four varieties: Estroven plus Multivitamin, Estroven Maximum Strength, Estroven Nighttime and Estroven plus Energy. All varieties are caplets. Take Estroven plus Multivitamin once a day with a meal or snack. You may take a one- or two-caplet-per-day formula of Estroven Maximum Strength. Estroven Nighttime is to be taken just before going to sleep at night. Take Estroven plus Energy at breakfast.