Adults (18 years and older): There is not enough scientific evidence available to recommend a specific dose of clove by mouth, on the skin, or by any other route. However, based on expert opinion, intake should not exceed 2.5 milligrams per kilogram of body weight each day. For anal fissures, a preparation of 1% clove oil cream for six weeks has been studied. For dental pain, a dose of 2 grams of homemade clove gel (made by grinding commercially available clove and mixing it with a clove-to-glycerin mixture in a ratio of 2:3) has been applied to inside the mouth for four minutes and then reapplied for another minute. As a mosquito repellent, a dose of 0.1 milliliters of clove oil of different concentrations (5, 10, 25, 50, 75, and 100%) per 30cm. of exposed skin has been studied.
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