Adults (18 years and older):There is no proven safe or effective dose for bloodroot (Sanguinaria canadensis) in adults. For gingivitis prevention, oral rinses containing 300 micrograms/milliliter of sanguinaria extract have been used twice daily for up to six months. For periodontal disease, oral rinses containing 0.01% sanguinarine have been used daily for up to six weeks to reduce plaque formation in patients with established and developing plaque and periodontal disease.
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