Rhubarb: Pyralvex has been used for decades as a salve for gingivitis and the oral mucosa; Parodium was introduced more recently as a similar treatment. Their active components both include rhubarb (Rheum palmatum) extract. The results from several clinical studies investigating Pyralvex and Parodium indicate that these combination treatments may be beneficial in treating gingivitis. However, additional study is needed in this area.
Avoid in individuals with a known allergy or hypersensitivity to rhubarb or its constituents. Anaphylaxis and rash have been reported. Rhubarb is not recommended in pregnant or breastfeeding women due to a lack of available scientific research. In theory, rhubarb may have uterine stimulant effects. Due to anthraquinone alkaloids, which are potentially mutagenic and genotoxic, rhubarb may be risky during breastfeeding. In case reports, rhubarb has also caused neonatal jaundice. Pregnant women considering taking rhubarb should consult with a qualified healthcare professional, including a pharmacist, to check for interactions.
Zinc: A few studies have reported significant reduction in plaque accumulation following treatment with zinc rinses and dentifrices. Preliminary research suggests that zinc citrate dentifrice may reduce the severity and occurrence of calculus formation. However, more well-designed studies are needed to confirm the effectiveness of zinc for plaque and gingivitis. More research may help to determine zinc's potential efficacy in other dental applications as well.
Zinc is generally considered safe when taken at the recommended dosages. Avoid zinc chloride since studies have not been done on its safety or effectiveness. Avoid with kidney disease. Use cautiously if pregnant or breastfeeding.
You should read product labels, and discuss all therapies with a qualified healthcare provider. Natural Standard information does not constitute medical advice, diagnosis, or treatment.
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