Two types of products -- lubricants and moisturizers -- can relieve vaginal dryness and itching. They can also make sexual intercourse (which in itself can stimulate natural lubrication) more comfortable. Lubricants, like Astroglide and K-Y Sensual Silk, are water-based and potential hydrogen (pH) neutral. They approximate the feel of vaginal secretions and provide temporary relief. Moisturizers, like K-Y Liquibeads and Replens, cling to the cells lining the vaginal wall for longer-lasting effectiveness. At least one clinical study has documented that Replens, like estrogen cream, increases the thickness of the vaginal lining.