Because focal dermal hypoplasia (FDH) is inherited, the only known risk factor is a family history of the disease. FDH is a rare condition, with only about 200 to 300 known cases worldwide. The exact incidence of the disorder is unknown. No racial or ethnic group is affected more than any other.
About 90% of people with FDH are female. Males with FDH generally die before birth. Individuals who are severely affected by FDH may die in infancy. Those who are mildly affected may have a normal life expectancy.
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