Alcohol in large amounts over a period of time can lead to alcoholic gastritis, which can irritate the GI tract and result in GI bleeding or ulcers. This risk is increased among alcohol users who also use nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, naproxen, and ibuprofen. There is a particular danger for heavy alcohol users who take amounts of these drugs over the recommended dosage. This can cause serious damage and bleeding in the GI tract. Acetaminophen is not an NSAID, but can be dangerous instead to the liver, especially when combined with alcohol. Alcohol users should consult a doctor about recommended dosage for pain relievers and interactions with alcohol.
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