The normal pancreas produces enzymes that are transported to the intestine to help the body digest food and absorb nutrients. If you have cystic fibrosis, the connection between your pancreas and intestine is blocked and the enzymes can not be transported. The result is poor digestion and nutrition, poor growth and weight gain, constipation and unpleasant odor from the stool. So, yes, you do need to take pancreatic enzymes by mouth to help improve your digestion. Talk to your doctor about this treatment option.