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Celiac disease and wheat allergy are two different conditions. Celiac disease is a permanent harmful reaction to gluten. Gluten is contained in some grains. The major grains that contain gluten are wheat, rye, and barley. Children with celiac disease will not lose their sensitivity to gluten and must avoid gluten-containing grains for life. Children with a wheat allergy have an adverse reaction to wheat protein. They need to avoid wheat but can eat other grains. Many children outgrow wheat allergies.