A Answers (3)
Stacy Wiegman, PharmD, Pharmacy, answeredHow well Lyrica relieves fibromyalgia pain seems to vary from person to person and may also depend on the dose and other factors. In one study, about 29% of people who took 450 milligrams (mg) of Lyrica a day for two months experienced at least a 50% reduction in pain from fibromyalgia, compared with only 13% of people who took a placebo (a sugar pill containing no medicine). Other research has shown that lower doses of Lyrica can provide some level of pain relief in people with fibromyalgia. In addition, studies show that Lyrica may improve sleep problems caused by fibromyalgia.
Collin Lee, PharmD, Pharmacy, answeredIn one study, researchers studied people with fibromyalgia who took either a placebo (a "sugar pill" that doesn't contain medicine) or Lyrica in varying dosages. At the end of eight weeks, the people who experienced the greatest pain relief were those who took 450 milligrams (mg) of Lyrica a day. Of these people, 29% of them reported at least a 50% improvement in pain, compared with only 13% of people taking the placebo.
In another study, doctors gave 750 people with fibromyalgia either a placebo or Lyrica in daily doses of 300 mg, 450 mg, or 600 mg. At the end of 14 weeks, all three doses of Lyrica proved to reduce pain better than placebo.
In both of these studies, people who took Lyrica also noted improvements in their overall sleep compared with people who took placebos. Work with your doctor to see if Lyrica is right for you and if so, to find the optimal dose for you.
Pfizer LYRICA™ (pregabalin) Team answeredIn clinical studies, LYRICA was proven to provide significant relief from fibromyalgia pain compared with a placebo, so patients felt better and could do more.*
In fibromyalgia clinical studies, some patients felt less pain in as soon as 1 week. For others it took longer.*
LYRICA may provide long-lasting relief from the chronic widespread pain of fibromyalgia. In a 6-month trial, most patients who were treated with LYRICA continued to feel fibromyalgia pain relief at the end of the trial.
*Individual results may vary.
This answer is sponsored by Pfizer. Any other answer is the responsibility of the party posting it. Any product information provided is intended only for residents of the U.S. Products may have different labeling in different countries.Please scroll for LYRICA™ indication.
Important Safety Information (ISI)
LYRICA is not for everyone. LYRICA may cause serious, even life threatening, allergic reactions. Stop taking LYRICA and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat or neck, or if you have any trouble breathing, or have a rash, hives or blisters.
Drugs used to treat seizures increase the risk of suicidal thoughts or behavior. LYRICA may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Patients, family members or caregivers should call the doctor right away if they notice suicidal thoughts or actions, thoughts of self harm, or any unusual changes in mood or behavior. These changes may include new or worsening depression, anxiety, restlessness, trouble sleeping, panic attacks, anger, irritability, agitation, aggression, dangerous impulses or violence, or extreme increases in activity or talking. If you have suicidal thoughts or actions, do not stop LYRICA without first talking to your doctor.
LYRICA may cause swelling of your hands, legs and feet, which can be serious for people with heart problems. LYRICA may cause dizziness and sleepiness. You should not drive or work with machines until you know how LYRICA affects you. Also, tell your doctor right away about muscle pain or problems along with feeling sick and feverish, or any changes in your eyesight including blurry vision, or if you have any kidney problems or get dialysis.
Some of the most common side effects of LYRICA are dizziness, blurry vision, weight gain, sleepiness, trouble concentrating, swelling of your hands and feet, dry mouth, and feeling “high.” If you have diabetes, tell your doctor about any skin sores.
You may have a higher chance for swelling and hives if you are also taking angiotensin converting enzyme (ACE) inhibitors so tell your doctor if you are taking these medications. You may have a higher chance of swelling of your hands or feet or gaining weight if you are also taking certain diabetes medicines. Do not drink alcohol while on LYRICA. You may have a higher chance for dizziness and sleepiness if you take LYRICA with alcohol, narcotic pain medicines, or medicines for anxiety.
Before you start LYRICA, tell your doctor if you are planning to father a child, or if you are pregnant, plan to become pregnant, or are breast-feeding. If you have had a drug or alcohol problem, you may be more likely to misuse LYRICA.
In studies, a specific type of blood vessel tumor was seen in mice, but not in rats. The meaning of these findings in humans is not known.
Do not stop taking LYRICA without talking to your doctor. If you stop suddenly you may have headaches, nausea, diarrhea, trouble sleeping, increased sweating, or you may feel anxious. If you have epilepsy, you may have seizures more often.
LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain, and pain after shingles. LYRICA is also indicated to treat partial onset seizures in adults with epilepsy who take 1 or more drugs for seizures.