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question

Can antidepressants cause adult onset seizures?

Univ. of Nev. School of Medicine, Family Medicine
Univ. of Nev. School of Medicine, Family Medicine
answer
Yes, there is a possibility that an antidepressant can cause seizures. Some of the older antidepressants include amitriptyline, bupropion, doxepin, maprotiline, mianserin, nomifensine, nortriptyline. The newer antidepressants are less likely to cause seizures but still have a risk of causing seizures. 

While antidepressant can cause seizures, they do not cause epilepsy or seizure disorders. Antidepressants make seizures more likely to occur if a person already has a disorder. This is known as "lowering the seizure threshold" and occurs with virtually all antidepressants. In some cases a seizure may be caused by these medicines alone, but do not occur again if the medicine is discontinued. One drug in particular, Buproprion, has been seen to cause seizures. It is marketed as Zyban (an aid to quit smoking) and Wellbutrin.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.