The following are the negative effects of hormone treatment:
- Breast tenderness or enlargement
- Vaginitis and vaginal itching
- Leg cramps
- Menstrual cramps
- Mood changes
The negative effects of hormone treatment vary considerably among women, and the severity and frequency differ as well. Some women have no negative effects; other women experience minor problems, while still others can't take the drugs because the unwanted effects are so strong.
The type of hormone treatment a woman is taking—estrogen only or a combination of estrogen plus progestogen—as well as the dose may determine the effects experienced. If you are having problems, it may be helpful to try a lower dose.