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Stacy Wiegman, PharmD, Pharmacy, answeredSpironolactone is a potassium-sparing diuretic which helps the kidneys process sodium and potassium correctly. Spironolactone can be classified in a group of drugs called aldosterone receptor antagonists, which lower the amount of aldosterone, a hormone responsible for balancing sodium and water levels in the body. Spironolactone can treat people with high blood pressure or low amounts of potassium in their bloodstream (hypokalemia). It can also treat swelling due to edema (retention of water) in people with congestive heart failure, nephrotic syndrome (a kidney disorder) or liver scarring caused by cirrhosis. As a diuretic, spironolactone works by producing more urine to eliminate excess sodium and maintain healthy potassium levels. Spironolactone has also been proven effective in treating precocious puberty (signs of puberty occurring in females under eight and males under nine years of sge) and a nervous system disorder called myasthenia gravis (MG). Ask your doctor about more uses of spironolactone.