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Mehmet Oz, MD, Cardiology, answeredThe hydroxycitric acid (HCA) extract from garcinia cambogia blocks fat by inhibiting citrate lyase, a key enzyme that your body needs to make fat from carbohydrates. Usually carbohydrates or sugars that are not used immediately or stored in other forms are converted into fats. When HCA inhibits citrate lyase, the fat-making process is halted and the production of LDL (bad cholesterol) and triglycerides decrease.Helpful? 8 people found this helpful.