It is not known whether iohexol is safe for pregnant or breastfeeding women, but its use during pregnancy or while breastfeeding is not recommended. Iohexol contains iodine, which has been shown to affect the thyroid health of a developing fetus. Also, X-rays involve radiation exposure, which may not be recommended if you are pregnant. If you are pregnant, you and your doctor should decide whether the potential benefits of undergoing an X-ray scan that involves iohexol outweigh the potential risks to your fetus. If you are breast-feeding and need to undergo an imaging scan that involves using iohexol as a contrast agent, you should not breastfeed for at least 24 hours after your doctor gives you iohexol.