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Approximately 20.9 million American adults, or about 9.5% of the U.S. population ages 18 and older in a given year, have a mood disorder. Mood disorders include major depressive disorder, dysthymic disorder, and bipolar disorder. Major depressive disorder affects approximately 14.8 million American adults, or about 6.7% of the U.S. population ages 18 and older in a given year. Major depressive disorder may be more prevalent in women than in men. However, we still don’t know if depression is truly less common among men or if men are less likely to recognize, acknowledge, and seek help.