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dLife - It's YOUR Diabetes Life! answeredCaffeine can raise blood sugar, even when you don't sweeten your coffee or drink diet drinks. Caffeine and stress are two common, sneaky, blood-sugar spikers that have nothing to do with carbohydrate. In fact, caffeine should be on any list of drugs that raise blood sugar. It's also possible to become more sensitive to caffeine's effects as time goes by, so if you like coffee, keep an eye on your blood sugar.