Major depression is a serious, chronic illness requiring medical treatment. Without treatment, clinical depression can cause professional and personal problems; social isolation; substance abuse; and suicide. People cannot ease the problem without proper treatment, and the symptoms usually do not go away on their own.
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Honor Society of Nursing (STTI) answered
Major depression is a serious medical illness that causes impairment in functioning in many areas of life. If left undiagnosed and untreated, major depression may result in suicide. The good news is that major depression is very treatable through medication and psychotherapy and improved mood and functioning can be restored. If you are suffering from major depression please seek help immediately from a medical or mental health professional.