Pediatric vasculitis occurs as a result of a variety of causes which lead to inflammation of various types of blood vessels.
Causes range from idiopathic(medical term for no known cause identfied) to being a result of hypersensitivity from drugs.Other causes include infections.It also occurs as part of many autoimmune disorders.
Inlammatory cells invade blood vessels.Immune complexes also play a key role in many syndromes of pediatric vasculitis.
Signs and symptoms are non-specific and include palapable purpura (raised patchy discolorations of the skin) and suggests involvement of small vessels or capillaries.
Medium vessel involvement often results in tender nodules and Large vessel vasculitis is found in chronic disorders such as Takayasu Arteritis which affects the Aorta and its major branches.
Kawasaki Disease and Henoch Schonlein Purpura are the most common forms of pediatric vasculitis.