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National Academy of Sports Medicine answeredDifferent blood pressure medications can have an impact on calculating target heart rate. If you are currently taking medication, please consult with your doctor regarding your heart rate while exercising. One of the more common blood pressure medication types is a beta blocker. A beta blocker works by blocking specific receptors which help to reduce the effects of the messengers which work to increase the heart rate. This allows the heart to maintain a slower rate and lowers the blood pressure. This slower rate will need to be factored into the calculation for determining your target heart rate. To find maximum heart rate for an individual not on a beta blocker, the calculation is 220-age. But, if an individual is on a beta blocker, they should follow the calculation of [162-(0.7xage) = estimated maximum heart rate]. For example, a 40 year old person on a beta blocker will have an estimated maximum heart rate of 134 beats per minute.Helpful? 3 people found this helpful.