There are many health risks related to consuming too much fructose in your daily diet. Some of the health risks involved in a high fructose diet are Diabetes, Insulin Resistance, Obesity, Metabolic Syndrome, and Heart Disease to name a few.
In general, making sure your diet includes a low intake of fructose (under 25 grams of fructose per day), and consuming most of your fructose from fruits and not processed packaged foods.
Fructose is metabolized by the liver. The liver has to work at 100% when you consume fructose as opposed to Glucose, where the liver has to work at 20%. Chronic intake or excessive intake of fructose over the course of your life has been shown to cause liver damage leading to liver cirrhosis or Non-Alcoholic Fatty Liver Disease (NAFLD).