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HIPEC (hyperthermic intraperitoneal chemoperfusion) can be appropriate for a wide variety of patients. In general, HIPEC is used for patients with appendix, colon, ovarian and gastric cancer. It is also used for rare diseases called pseudomyxoma peritonei and mesothelioma. In general, the cancer needs to be limited to the abdominal cavity for HIPEC to be used. HIPEC may be the only treatment needed or can be combined with traditional chemotherapy as well. Patients need to be relatively healthy otherwise as the procedure can be long and complex. Another key feature is the ability to remove all of the visible cancer and then administer the chemotherapy. If the disease is too extensive then HIPEC may not be able to be done.