The tendons of the thumb move through a narrow space or tunnel at the wrist. The tendons must move smoothly within this space as well as within the synovial lining the surrounds these tendons. In cases of De Quervain’s disease, the synovial lining becomes inflamed, limiting the movement of the tendons through this tunnel. The individual will likely suffer from aching pain in the thumb, wrist, and forearm and weakness of the thumb and should see a physician for proper evaluation and treatment. De Quervain’s disease is also known as Hoffman’s disease.
(This answer provided for NATA by the Eastern University Athletic Training Education Program.)