If you have had hepatitis (inflammation of the liver) caused by a virus, or unexplained jaundice (yellow discoloration of the skin), since age 11, you are not eligible to donate blood. This includes those who have had hepatitis with Cytomegalovirus (CMV), or Epstein-Barr Virus (EBV), the virus that causes Mononucleosis.
It is acceptable to donate blood if you have had jaundice or hepatitis caused by something other than a viral infection, for example: medications, Gilbert’s disease, bile duct obstruction, alcohol, gallstones or trauma to the liver.
If you have ever tested positive for hepatitis B or hepatitis C, at any age, you are not eligible to donate, even if you were never sick or jaundiced from the infection.
Guidelines on eligibility to give blood change from time to time. The most up-to-date eligibility information can be obtained by contacting the American Red Cross blood center nearest you.