A Answers (2)
Connective tissues significantly affect the aorta because the aorta is exposed to high shear stress, or pressure from the constant flow of blood.
Allan Stewart, MD, Cardiothoracic Surgery, answered on behalf of Columbia University Department of Surgery
Connective tissue disorders significantly affect the aorta. The reason is because the aorta is essentially a tube that carries blood throughout the body. It is exposed to high shear stress. This pressure will ultimately expand the wall, if the structure (connective tissue) is abnormal. Think of it is a weakened piece of pipe. If the pressure in that pipe is high, the pipe will ultimately burst. It is not particularly different with the aorta.