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Mehmet Oz, MD, Cardiology, answeredAlso referred to as baby aspirin, low-dose aspirin has been shown to lower blood pressure when consumed before bedtime. Be sure to take this over-the-counter medication with 8 ounces of water. Drink half the glass before and half the glass after you swallow the aspirin to avoid stomach irritation. If you have a bleeding disorder or have a history of stomach ulcers, be sure to check with your doctor first.