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William J Resh, MD
Location and Office HoursLas Vegas Cardiology
7241 W Sahara
Las Vegas, NV 89117
- Anthem/HMO Nevada (BC/BS)
- Sunrise Hospital & Medical Center
What are acyanotic heart defects?
Healthwise answeredAcyanotic heart defects are heart problems that develop before or at birth but do not normally interfere with the amount of oxygen or blood that reaches the body's tissues. Acyanotic heart defects include ventricular septal defect (VSD), atrial septal defect (ASD), patent ductus arteriosus (PDA), pulmonary valve stenosis, aortic valve stenosis and coarctation of the aorta. Acyanotic heart defects do not usually cause cyanosis, a bluish tint to the skin, lips and nail beds due to reduced oxygen flow. If cyanosis develops in a person with acyanotic heart defects, it is typically a result of increased activity (such as crying and feeding) during which more oxygen is needed.
What medications are used to treat anomalous coronary arteries or fistulas?
Sometimes children are born with an abnormal placement of the arteries that supply the heart with blood (the coronary arteries). Abnormal branches from the coronary arteries (called fistulas) may be present.
Treatment of anomalous coronary arteries and fistulas may consist of a combination of surgery, procedures, and/or medications. Medications are used to treat symptoms of congestive heart failure. The following medications are commonly prescribed to treat this form of congenital (present at birth) heart disease:
- Diuretics: The most commonly prescribed diuretics are furosemide (Lasix) and thiazides (Diuril and Hydrodiuril). Diuretics act to cause the child to pass more urine, leading to a smaller blood volume - and a smaller burden on the heart to pump. Another commonly used diuretic is spironolactone (Aldactone). It has a weak diuretic effect and is mainly used because it helps the kidneys retain potassium. Other diuretics tend to waste potassium excessively. Spironolactone may also help with heart remodeling via mechanisms that are not completely known yet.
- Inotropes: These medications, which include digoxin, help the heart pump more efficiently (stronger while using less energy).
- Afterload-reducing agents: Many of the medications in this category end with -pril. These drugs, which include captopril, are sometimes used in the treatment of congestive heart failure. When used, they act to help blood flow to the body and tissues. The may also help with heart remodeling via mechanisms that are not completely known yet.
- Beta blockers: Many of the medications in this category end with -olol. These medications may help to regulate the stress response of the body to congestive heart failure (neurohormonal regulation).
How is coronary artery disease (CAD) different for women than for men?
In general, men are more likely to develop coronary artery disease than women. This is because, until they go through menopause, women benefit from higher levels of estrogen in their bloodstream. However, once women go through menopause, their rate of developing the disease exceeds men's. After the age of 70, more women die of coronary artery disease than men.Helpful? 1 person found this helpful.
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