The kidneys regulate blood pressure by secreting hormones that can increase blood pressure. Narrowing of the kidney arteries (renal artery disease) can restrict blood flow to the kidneys. In response, the kidneys may secrete more hormones to raise blood pressure in hopes of improving kidney blood flow. In this manner, renal artery disease can promote high blood pressure. Paradoxically, high blood pressure can contribute to the formation of the atherosclerotic plaque, which typically causes renal artery disease.
Nicholas DiDomenico, MD
Specialty: Internal Medicine
- internal medicine
Location and Office HoursValley Internal Medicine
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- How are high blood pressure and renal artery disease linked?
What is renal (kidney) artery disease?
“Renal” is another word for kidney, and “renal artery disease” refers to blockages in the arteries that supply blood to your kidneys. Renal artery disease can be made worse by high blood pressure and other atherosclerotic risk factors. In some cases, renal artery disease can be a cause of high blood pressure. In severe cases, it can also lead to kidney failure. About 5 percent of all patients with high blood pressure have blockages in the renal arteries, and at least 30 percent of patients who have blockages in other arteries also have blockages in their renal arteries.Helpful? 1 person found this helpful.
What causes nephrotic syndrome?
Nephrotic syndrome is caused by damage to the tiny blood vessels in the kidney that filter waste and excess water from the blood.
Many conditions and diseases can cause nephrotic syndrome, including:
- Minimal change disease (also called nil disease), a type of kidney disease. The cause of minimal change disease is unknown. But this disease causes most of the cases of nephrotic syndrome in children.
- Membranous glomerulopathy and focal segmental glomerulosclerosis, which are two other diseases of the kidney. Both of these diseases affect the glomeruli. The glomeruli help filter waste out of your blood. In focal segmental glomerulosclerosis, some of the parts of the glomeruli have scar tissue. This can affect how they filter the blood. In membranous glomerulopathy, the tissue wall (membrane) that separates blood and urine and acts as a filter in your kidney becomes thickened and damaged.
- Diabetes and lupus. Diabetes is the most common cause of nephrotic syndrome in adults.
- Infections, such as HIV, hepatitis B, or hepatitis C.
- Medicines, such as nonsteroidal anti-inflammatory drugs, penicillamine, gold therapy or captopril.
- Illegal drugs, such as heroin.
- Conditions such as preeclampsia, chronic graft rejection following an organ transplant, and allergic reactions to bee stings.
- Unknown (idiopathic) factors.
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