Hemorrhaging disorders are most often inherited. Males are more at risk for inheriting these disorders, though females do rarely inherit them. Race and ethnicity don't seem to be a factor in whether or not someone inherits a hemorrhaging disorder.
Joseph D McCracken, MD
- internal medicine
Location and Office HoursCancer Care Center of Texas
San Antonio, TX 78212
- Community First Health Plans
- Humana Health Plan
- UNICARE Health Plans of Texas
- United Healthcare
- Baptist Medical Center
- CHRISTUS Santa Rosa City Centre & Children's Hospital
- Metropolitan Methodist Hospital
- Nix Medical Center
- Nix Specialty Health Center
- South Texas Regional Medical Center
Who is most at risk for a hemorrhaging disorder?
Piedmont Heart Institute answered
What are B cells and T cells?
Anthony Komaroff, MD, Internal Medicine, answeredB cells and T cells are lymphocytes (white blood cells). Each has a different way of fighting infection. B and T cells start life in the bone marrow. B cells are homebodies and stay in the marrow to mature. T cells, on the other hand, leave the bone marrow early and move to the thymus, an important organ of the lymphatic system located in the upper chest. The young T cells mature in the thymus (hence the "T" in T cell). After they reach maturity, B and T cells travel via the bloodstream to the peripheral lymphoid tissues -- lymph nodes, spleen, tonsils, adenoids, appendix, and so on -- where some remain. The others circulate in the blood, migrating from one lymphoid organ to another.
What is transfusion-related acute lung injury (TRALI)?
American Red Cross answered
Transfusion-related acute lung injury (TRALI) is a serious blood transfusion complication thought to be most commonly caused by a reaction to white blood cell antibodies present primarily in the plasma component of blood products. When transfused, these antibodies sometimes activate a type of white blood cell called a granulocyte, which causes plasma to leak into the lungs, resulting in fluid accumulation – a condition referred to as acute pulmonary edema. Plasma containing blood components obtained from certain donors are thought to carry a higher risk of causing TRALI. Donors who are more likely to have these antibodies include women who have been pregnant and developed these antibodies as a result of exposure to fetal blood and donors who have previously received a transfusion or transplant.
There are currently no screening tests to prevent TRALI, nor is there any single intervention that can eliminate the risk of TRALI. However, some steps to reduce the risk of TRALI are being taken for products that contain high volumes of plasma which may contain antibodies to white blood cells.
See all Blood Basics questions