Numbness is often a feature of peripheral neuropathy, and this can affect the body's ability to protect itself. For example, you may not be aware of an injury because you will be unable to feel the body's warning sign: pain. This can lead to infection and amputation, especially in those with diabetes. Chronic pain can also be a result, too. Damage to the body's more important nerves can be even more severe. You may suffer from life-threatening complications if the peripheral neuropathy affects your breathing or heartbeat. This kind of damage may also make you experience trouble eating and digesting food. Blood pressure may be lowered, and sexual function may be impaired. Loss of muscle control may make daily chores more difficult and accidents more likely.
John A. Popp, MD
Location and Office HoursStanford Medical Center
300 Pasteur Dr
Stanford, CA 94305
- Anthem BlueCross BlueShield
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- Capital District Physicians' Health Plan (CDPHP)
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- Brigham & Women's Hospital
How does peripheral neuropathy affect the body?
Honor Society of Nursing (STTI) answeredHelpful? 2 people found this helpful.
How can low serotonin levels affect me?
Sharine Forbes, Gerontology, answeredSerotonin, which has been shown to influence many of the brains cells, is made through a biochemical process in the brain. As a neurotransmitter, serotonin is responsible for feelings of happiness, contentment, and controls overall mood. When concentration levels of serotonin are high, feelings of happiness ensue. When levels of serotonin are low, an individual’s overall mood decreases as they become irritable and sad. The overall composition of serotonin is essentially a combination of tryptophan hydroxylase and tryptophan, which makes 5-hydoxytryptamine (5-HTP), also known as serotonin. Despite its place of origin, it is for the most part found in the digestive tract and in the blood platelets. Additionally, 5-hydoxytryptamine (5-HTP), which can act as a serotonin precursor, stimulates the secretion of serotonin production in the brain. If the levels of serotonin absorbed during reuptake are extreme, this also can lead to feelings of sadness. As a result, serotonin is linked to have influences on different behaviors such as, but not limited to, overall mood.
What is the best treatment option for neuropathy in the feet?
Treatment falls into two categories: symptomatic treatment for any uncomfortable tingling or burning and treatment of the underlying cause.
For symptomatic treatment there are many medications that are used. One of the most common and most effective was originally an anti-seizure medication and pain medication for the pain one has after getting the shingles. This is gabapentin and there is a close cousin to this medication called pregabalin that is also used a great deal. Other anti-seizure, anti-depressant and, on occasion, narcotic pain medications are used as well. If a patient has intolerable side effects or the oral medications are not working, neuropathy creams can also be tried. Pain patches can also be tried in those hard to treat patients.
Treating the underlying disorder is also very important. For the most common cause of neuropathy, diabetes, good glucose control is paramount. This will help the neuropathy stabilize. Other potentially reversible causes can include folate, B12 deficiencies, thyroid disorders, medication side effects (especially chemotherapeutic agents), paraneoplastic disorders and blood diseases like monoclonal gammopathies (multiple myeloma being the most worrisome). A thorough workup by a neurologist is advised if you develop numbness, tingling or burning in the feet.Helpful? 6 people found this helpful.
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