A spate of recent laboratory studies supports the participation of mast cells in atherosclerosis and in arterial aneurysm formation. Most of these studies derived from observations in mice and using biomarkers of mast cell activation in humans. But direct evidence that mast cells aggravate human cardiovascular disease remains scant. General advice is to heed current guidelines regarding cardiovascular prevention assiduously to minimize any excess risk you might have from an underlying mast cell activation disorder.
Galen Centeno, MD
Specialty: Internal Medicine
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Dunellen, NJ 08812
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Can a mast cell activation disorder make heart disease worse?
Brigham and Women's Hospital answered
What is celiac sprue (gluten sensitivity)?
Bill Salt, MD, Gastroenterology, answeredCeliac sprue, or gluten-sensitive enteropathy, is a disorder caused by a specific sensitivity to the grain products wheat, barley, rye and oats. New research conducted at the University of Maryland shows that as many as one in every 150 people in the United States may have celiac sprue. Having a family member with the diagnosis increases the likelihood that you will have it, as does having diarrhea and/or iron deficiency anemia. A blood test is available to screen for the condition.
Find out more about this book:Irritable Bowel Syndrome & the MindBodySpirit Connection: 7 Steps for Living a Healthy Life with a Functional Bowel Disorder, Crohn's Disease, or Colitis (Mind-Body-Spirit Connection Series.)
Is there a connection between celiac disease and type 2 diabetes?
dLife - It's YOUR Diabetes Life! answeredThere is no correlation between type 2 diabetes and celiac disease. The prevalence of celiac disease among people with type 2 diabetes is the same as for the general population, which is about 1 percent.
However, the prevalence of celiac disease is higher among people with type 1 diabetes. Approximately 8 to 10 percent of people with type 1 diabetes also have celiac disease. Researchers don't know for sure why the prevalence of celiac disease is higher among people with type 1 diabetes, but they think it probably has something to do with the fact that both diseases are autoimmune conditions, and so they may share genetic similarities. Every person with type 1 diabetes should be tested for celiac disease so they can go on a gluten-free diet if necessary. If people with celiac disease continues to eat gluten, they are at risk for developing other complications such as osteopenia, osteoporosis, iron deficiency anemia, fatigue, and more serious complications such as intestinal cancers.
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