Hirschsprung disease (HD) is a disease of the large intestine.
The large intestine is also known as the colon. The word bowel refers to the large and small intestines. HD usually occurs in children. It causes constipation, which means that bowel movements are difficult. Some children with HD cannot have bowel movements at all. The stool creates a blockage in the intestine.
If HD is not treated, stool can fill up the large intestine. This can cause serious problems like infection, bursting of the colon, and even death.
This answer is based on source information from The National Digestive Disease Information Clearinghouse (NDDIC).