Coronary heart disease is the hardening of arteries from plaque build-up. The hardened arteries restrict blood flow, so your heart cannot receive enough oxygenated blood, especially when it beats quickly during physical exertion or stress. This can cause chest pain and shortness of breath. If an artery becomes completely blocked, a heart attack may occur. Lack of oxygen to your heart during a heart attack causes irreversible damage as the heart muscle dies and is replaced with scar tissue. If damage is severe, the heart may be unable to pump enough blood through the body, a condition called heart failure. Life-threatening irregular heartbeats known as arrhythmias can also occur.
Anthony T. Scardella, MD
Specialty: Internal Medicine
- internal medicine
- pulmonary & respiratory medicine
Location and Office HoursRobert Wood Johnson University Hospital
1 Robert Wood Johnson
New Brunswick, NJ 08901
- Robert Wood Johnson University Hospital
- Saint Peter's University Hospital
- Somerset Medical Center
How does coronary heart disease affect the body?
Piedmont Heart Institute answered
What increases my risk for nephrotic syndrome?
Diabetes is the most common cause of nephrotic syndrome in adults.
You also have an increased risk of developing nephrotic syndrome if you have a disease that results in an impaired immune system, such as HIV or lupus.
Nephrotic syndrome is a relatively rare disease that can occur at any age.
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What are the different types of Crohn's disease?
There are five different types of Crohn's disease, depending on location. By far, the most common location for Crohn's disease is in the terminal ileum (the last part of the small bowel). In fact, historically, it used to be called terminal ileitis. About 35% of people with Crohn’s disease will have only terminal ileal involvement. However, another 35% of people will have disease that's limited to both their small bowel as well as the first third of their colon.
About 20% of people will have Crohn's colitis, which means it involves only the colon, not the small bowel.
About 10% of people have Crohn's disease that involves the proximal gastrointestinal tract, which includes the upper part of the ileum, the jejunum (the middle section of the small bowel), the stomach or the duodenum (the first part of the small bowel). This can also represent a very aggressive form of Crohn's disease that oftentimes requires more aggressive treatments to get under control.
Additionally, up to 30% of people with Crohn’s disease at other locations can also develop perianal disease, which comprises abnormal connections from the last part of the colon, the rectum, to the outer part of the skin around the anus with fistulas. These abnormal connections from either deep ulcerations or active disease can burrow through the rectum, through the muscles and the fat around the rectum, and can lead to the formation of abscesses as well as fistulas. Often, treatment requires a combination approach with surgery, antibiotics and medications.
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